AZD1446 free base, CAS 1025007-04-8

AZD1446 free base, CAS 1025007-04-8, Stock 188g, Assay 99.5%, White powder, Water 0.19%, Single Impurity 0.5%.

AZD1446 free base

AZD1446, also known as TC-6683, is a novel highly selective α4β2 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders. AZD1446 showed favorable pharmaceutical properties and in vivo efficacy in animal models has been identified as a potential treatment for cognitive deficits associated with psychiatric or neurological conditions and had been evaluated in phase 2 clinical trials as a treatment for Alzheimer's disease.

Product Details:

Name: AZD1446 free base

CAS#: 1025007-04-8 (free base)

Chemical Formula: C11H13ClN2O2

Exact Mass: 240.0666

Molecular Weight: 240.69

Elemental Analysis: C, 54.89; H, 5.44; Cl, 14.73; N, 11.64; O, 13.29

Specification:

Synonym: AZD 1446, AZD-1446, AZD1446, TC 6683, TC-6683, TC6683

IUPAC/Chemical Name: 3-(5-Chloro-2-furoyl)-3,7-diazabicyclo(3.3.0)octane

InChi Key: GTUIQNHJSXQMKW-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H13ClN2O2/c12-10-2-1-9(16-10)11(15)14-5-7-3-13-4-8(7)6-14/h1-2,7-8,13H,3-6H2

SMILES Code: O=C(N1CC2CNCC2C1)C3=CC=C(Cl)O3

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years)

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: