KRA-533, CAS 10161-87-2

KRA-533, CAS 10161-87-2, Stock 327g, Assay 99.5%, White powder, Water 0.39%, Single Impurity 0.5%.

KRA-533

KRA-533 is a novel KRAS Agonist, binding the GTP/GDP-binding pocket of KRAS, preventing the cleavage of GTP into GDP, leading to the accumulation of GTP-KRAS, an active form of KRAS.

Product Details:

Name: KRA-533

CAS#: 10161-87-2

Chemical Formula: C13H16BrNO3

Exact Mass: 313.0314

Molecular Weight: 314.179

Elemental Analysis: C, 49.70; H, 5.13; Br, 25.43; N, 4.46; O, 15.28

Specification:

Synonym: KRA-533; KRA 533; KRA533

IUPAC/Chemical Name: 4-{4-[(Bromoacetyl)amino]butyl}benzoic acid

InChi Key: WZQJLTLURXNPQG-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H16BrNO3/c14-9-12(16)15-8-2-1-3-10-4-6-11(7-5-10)13(17)18/h4-7H,1-3,8-9H2,(H,15,16)(H,17,18)

SMILES Code: O=C(O)C1=CC=C(CCCCNC(CBr)=O)C=C1

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: