15811125 CAS 1293281-49-8: Seltorexant

CAS 1293281-49-8: Seltorexant

  • CAS 1293281-49-8: Seltorexant

CAS 1293281-49-8: Seltorexant
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1293281-49-8
  • Stock: 228g
  • Assay: 99.39%

Seltorexant, CAS 1293281-49-8

Seltorexant, CAS 1293281-49-8, Stock 228g, Assay 99.39%, White powder, Water 0.39%, Single Impurity 0.22%.


Seltorexant

Seltorexant, also known as JNJ-42847922 and MIN-202, is a potent OX2R antagonist that has been shown to promote sleep in various species. JNJ-42847922 had an approximate 2-log selectivity ratio versus the human orexin-1 receptor. Ex vivo receptor binding studies demonstrated that JNJ-42847922 quickly occupied OX2R binding sites in the rat brain after oral administration and rapidly cleared from the brain. Seltorexant shows antidepressant and sleep-promoting effects in patients with major depressive disorder. JNJ-42847922 induces somnolence in healthy subjects without residual central effects.


Product Details:

Name: Seltorexant

CAS#: 1293281-49-8

Chemical Formula: C21H22FN7O

Exact Mass: 407.187

Molecular Weight: 407.4534

Elemental Analysis: C, 61.90; H, 5.44; F, 4.66; N, 24.06; O, 3.93


Specification:

Synonym: Seltorexant; JNJ-42847922; JNJ 42847922; JNJ42847922; MIN-202; MIN 202; MIN202

IUPAC/Chemical Name: ((3aR,6aS)-5-(4,6-dimethylpyrimidin-2-yl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)methanone

InChi Key: SQOCEMCKYDVLMM-IYBDPMFKSA-N

InChi Code: InChI=1S/C21H22FN7O/c1-13-8-14(2)26-21(25-13)28-11-15-9-27(10-16(15)12-28)20(30)19-17(22)4-3-5-18(19)29-23-6-7-24-29/h3-8,15-16H,9-12H2,1-2H3/t15-,16+

SMILES Code: O=C(N1C[C@@](CN(C2=NC(C)=CC(C)=N2)C3)([H])[C@@]3([H])C1)C4=C(N5N=CC=N5)C=CC=C4F

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: