CAS 932372-01-5: Asapiprant
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- CAS Number: 932372-01-5
- Stock: 648g
- Assay: 98.39%
Asapiprant, CAS 932372-01-5
Asapiprant, CAS 932372-01-5 , Stock 648g, Assay 98.39%, White powder, Water 0.15%, Single Impurity 0.87%.
Asapiprant
Asapiprant, also known as S-555739, is a the potent and selective DP1 receptor antagonist. Asapiprant exhibited high affinity and selectivity for the DP1 receptor. Significant suppression of antigen-induced nasal resistance, nasal secretion, and cell infiltration in nasal mucosa was observed with asapiprant treatment. In addition, treatment with asapiprant suppressed antigen-induced asthmatic responses, airway hyper-responsiveness, and cell infiltration and mucin production in lung. These results show that asapiprant is a potent and selective DP1 receptor antagonist, and exerts suppressive effects in the animal models of allergic diseases. Thus, asapiprant has potential as a novel therapy for allergic airway diseases.
Product Details:
Name: Asapiprant
CAS#: 932372-01-5
Chemical Formula: C24H27N3O7S
Exact Mass: 501.157
Molecular Weight: 501.554
Elemental Analysis: C, 57.47; H, 5.43; N, 8.38; O, 22.33; S, 6.39
Specification:
Synonym: S-555739; S 555739; S555739; Asapiprant
IUPAC/Chemical Name: 2-(5-(4-((4-isopropoxyphenyl)sulfonyl)piperazin-1-yl)-2-(oxazol-2-yl)phenoxy)acetic acid
InChi Key: ZMZNWNTZRWXTJU-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H27N3O7S/c1-17(2)34-19-4-6-20(7-5-19)35(30,31)27-12-10-26(11-13-27)18-3-8-21(24-25-9-14-32-24)22(15-18)33-16-23(28)29/h3-9,14-15,17H,10-13,16H2,1-2H3,(H,28,29)
SMILES Code: O=C(O)COC1=CC(N2CCN(S(=O)(C3=CC=C(OC(C)C)C=C3)=O)CC2)=CC=C1C4=NC=CO4
Appearance: White powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
Certifications:

