Asapiprant, CAS 932372-01-5

  • Asapiprant, CAS 932372-01-5

Asapiprant, CAS 932372-01-5
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 932372-01-5
  • Stock: 648g
  • Assay: 98.39%

Asapiprant, CAS 932372-01-5 

Asapiprant, CAS 932372-01-5 , Stock 648g, Assay 98.39%, White powderWater 0.15%, Single Impurity 0.87%.


Asapiprant

Asapiprant, also known as S-555739, is a the potent and selective DP1 receptor antagonist. Asapiprant exhibited high affinity and selectivity for the DP1 receptor. Significant suppression of antigen-induced nasal resistance, nasal secretion, and cell infiltration in nasal mucosa was observed with asapiprant treatment. In addition, treatment with asapiprant suppressed antigen-induced asthmatic responses, airway hyper-responsiveness, and cell infiltration and mucin production in lung. These results show that asapiprant is a potent and selective DP1 receptor antagonist, and exerts suppressive effects in the animal models of allergic diseases. Thus, asapiprant has potential as a novel therapy for allergic airway diseases.


Product Details:

Name: Asapiprant

CAS#: 932372-01-5

Chemical Formula: C24H27N3O7S

Exact Mass: 501.157

Molecular Weight: 501.554

Elemental Analysis: C, 57.47; H, 5.43; N, 8.38; O, 22.33; S, 6.39


Specification:

Synonym: S-555739; S 555739; S555739; Asapiprant

IUPAC/Chemical Name: 2-(5-(4-((4-isopropoxyphenyl)sulfonyl)piperazin-1-yl)-2-(oxazol-2-yl)phenoxy)acetic acid

InChi Key: ZMZNWNTZRWXTJU-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H27N3O7S/c1-17(2)34-19-4-6-20(7-5-19)35(30,31)27-12-10-26(11-13-27)18-3-8-21(24-25-9-14-32-24)22(15-18)33-16-23(28)29/h3-9,14-15,17H,10-13,16H2,1-2H3,(H,28,29)

SMILES Code: O=C(O)COC1=CC(N2CCN(S(=O)(C3=CC=C(OC(C)C)C=C3)=O)CC2)=CC=C1C4=NC=CO4

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: