CAS 722533-56-4: Elacestrant
(World's Largest Pharmaceutical Supplier)
- CAS Number: 722533-56-4
- Stock: 426g
- Assay: 98.42%
Elacestrant, CAS 722533-56-4
Elacestrant, CAS 722533-56-4, Stock 426g, Assay 98.42%, White powder, Water 0.23%, Single Impurity 0.21%.
Elacestrant
Elacestrant, also known as RAD1901, is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Upon oral administration of higher doses of RAD1901, this agent acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This may inhibit the growth and survival of ER-expressing cancer cells. At lower doses of this agent, RAD1901 acts as a SERM and has estrogen-like effects in certain tissues, which can both reduce hot flashes and protect against bone loss. In addition, RAD1901 is able to cross the blood-brain barrier (BBB).
Product Details:
Name: Elacestrant free base
CAS#: 722533-56-4 (free base)
Chemical Formula: C30H38N2O2
Exact Mass: 458.2933
Molecular Weight: 458.646
Elemental Analysis: C, 78.56; H, 8.35; N, 6.11; O, 6.98
Specification:
Related CAS #: 1349723-93-8 (HCl) 722533-56-4 (free base)
Synonym: RAD1901; RAD-1901; RAD 1901; RAD1901; Elacestrant; Elacestrant free base
IUPAC/Chemical Name: (R)-6-(2-(ethyl(4-(2-(ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol
InChi Key: SIFNOOUKXBRGGB-AREMUKBSSA-N
InChi Code: InChI=1S/C30H38N2O2/c1-4-31-17-16-22-6-8-23(9-7-22)21-32(5-2)30-20-28(34-3)14-15-29(30)26-11-10-25-19-27(33)13-12-24(25)18-26/h6-9,12-15,19-20,26,31,33H,4-5,10-11,16-18,21H2,1-3H3/t26-/m1/s1
SMILES Code: OC1=CC=C2C[C@H](C3=CC=C(OC)C=C3N(CC)CC4=CC=C(CCNCC)C=C4)CCC2=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
Certification:
