15830272 483313-22-0: SB 674042

483313-22-0: SB 674042

  • 483313-22-0: SB 674042

483313-22-0: SB 674042
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 483313-22-0
  • Stock: 6g
  • Assay: 98.00%

483313-22-0: SB 674042

483313-22-0, SB 674042Stock 6g, Assay 98.00%, White to off-white powder.


SB 674042

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd=5.03 nM), exhibits 100-fold selectivity for OX1 over OX2 receptors with IC50 values of 3.76 nM and 531 nM, respectively


Product Details:

Name: SB-674042

CAS#: 483313-22-0

Chemical Formula: C24H21FN4O2S

Molecular Weight: 448.51


Specification:

Synonym: SB-674042;(S)-1-[5-[2-Fluorophenyl]-2-methylthiazol-4-yl]-1-[2-[[5-phenyl-[1,3,4]oxadiazol-2-yl]methyl]pyrrolidin-1-yl]methanone;(2S)-1-[[5-(2-Fluorophenyl)-2-methyl-4-thiazolyl]carbonyl]-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-pyrrolidine(9CI);[5-(2-Fluorophenyl)-2-methyl-4-thiazolyl][2(S)-2-[(5-phenyl-1,3,4-oxadChemicalbookiazol-2-yl)methyl-1-pyrrolidinyl]methanone;SB674042;SB674042;[5-(2-FLUOROPHENYL)-2-METHYL-1,3-THIAZOL-4-YL]-[(2S)-2-[(5-PHENYL-1,3,4-OXADIAZOL-2-YL)METHYL]PYRROLIDIN-1-YL]METHANONE;SB-674042,CID10204153;Methanone,[5-(2-fluorophenyl)-2-methyl-4-thiazolyl][(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-1-pyrrolidinyl]-

SMILES Code: FC1=C(C2=C(C(N3[C@H](CC4=NN=C(C5=CC=CC=C5)O4)CCC3)=O)N=C(C)S2)C=CC=C1

Appearance: White to off-white solid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certification: