CAS 192185-72-1: Tipifarnib
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- CAS Number: 192185-72-1
- Stock: 277g
- Assay: 99.49%
Tipifarnib, CAS: 192185-72-1
Tipifarnib, CAS: 192185-72-1, Stock 277g, Assay 99.49%, White powder, EOS is one of TOP GMP manufacturer
Tipifarnib
Tipifarnib is a farnesyltransferase inhibitor and has been investigated as a potential treatment for various cancers, including acute myeloid leukemia, lymphoma, and solid tumors. Studies have shown that tipifarnib can inhibit the growth and proliferation of cancer cells by blocking the farnesylation of key signaling proteins, which disrupts their function and ultimately leads to cell death.
Product Details:
Name: Tipifarnib
CAS#: 192185-72-1
Chemical Formula: C27H22Cl2N4O
Exact Mass: 488.11707
Molecular Weight: 489.4
Elemental Analysis: C, 66.26; H, 4.53; Cl, 14.49; N, 11.45; O, 3.27
Specification:
Synonym: R115777; R 115777; R-115777; LX81; NSC702818; D03720; Tipifarnib; trade name Zarnestra
IUPAC/Chemical Name: (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
InChi Key: PLHJCIYEEKOWNM-HHHXNRCGSA-N
InChi Code: InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1
SMILES Code: O=C1N(C)C2=C(C=C([C@@](C3=CC=C(Cl)C=C3)(N)C4=CN=CN4C)C=C2)C(C5=CC=CC(Cl)=C5)=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
HS Tariff Code: 2934.99.9001
