CAS 160800-57-7: Auristatin E
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- CAS Number: 160800-57-7
- Stock: 131g
- Assay: 98.44%
Auristatin E, CAS 160800-57-7:
Auristatin E, CAS 160800-57-7, Stock 131g, Assay 98.44%, White powder, Water 0.21%, Single Impurity 0.14%.
Auristatin E
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; it is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent that inhibits tubulin polymerization. Auristatin E-antibody conjugates have proven to be successful anticancer agents.
Product Details:
Name: Auristatin E
CAS#: 160800-57-7
Chemical Formula: C40H69N5O7
Exact Mass: 731.5197
Molecular Weight: 732.02
Elemental Analysis: C, 65.63; H, 9.50; N, 9.57; O, 15.30
Specification:
Synonym: Auristatin E
IUPAC/Chemical Name: (S)-2-((S)-2-(dimethylamino)-3-methylbutanamido)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethylbutanamide
InChi Key: WOWDZACBATWTAU-FEFUEGSOSA-N
InChi Code: InChI=1S/C40H69N5O7/c1-14-26(6)35(44(11)40(50)33(24(2)3)42-39(49)34(25(4)5)43(9)10)31(51-12)23-32(46)45-22-18-21-30(45)37(52-13)27(7)38(48)41-28(8)36(47)29-19-16-15-17-20-29/h15-17,19-20,24-28,30-31,33-37,47H,14,18,21-23H2,1-13H3,(H,41,48)(H,42,49)/t26-,27+,28+,30-,31+,33-,34-,35-,36+,37+/m0/s1
SMILES Code: O[C@H]([C@@H](C)NC([C@H](C)[C@@H](OC)[C@H]1N(C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C)=O)=O)=O)CCC1)=O)C2=CC=CC=C2
Appearance: Solid powder
Purity: >95% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
Certification:
