CAS 1190305-31-7 | ARHA-007 : Arhalofenate
(World's Largest Pharmaceutical Supplier)

CAS 1190305-31-7 is a chemical compound that is commonly used in the pharmaceutical industry. It is also known as (S)-4-(4-(3,4-dichlorophenyl)-1H-imidazol-1-yl)-N,N-dimethyl-2-(2-methylpropyl)pentanamide. This compound belongs to the class of imidazole derivatives and has a molecular weight of 472.98 g/mol.

Chemical Properties

CAS 1190305-31-7 is a white to off-white solid that is soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO). It has a melting point of 96-99°C and a boiling point of 689.6°C at 760 mmHg. This compound is stable under normal conditions and does not react with water or air.

CAS 1190305-31-7 has several pharmaceutical applications. It is a selective and potent inhibitor of the human histone deacetylase 6 (HDAC6) enzyme, which is involved in the regulation of gene expression. HDAC6 inhibitors have been shown to have therapeutic potential in the treatment of various diseases, such as cancer, neurodegenerative disorders, and inflammatory diseases.

In addition, CAS 1190305-31-7 has been used as a reference standard in the development of analytical methods for the quantitative determination of HDAC6 inhibitors in biological samples. It has also been used in preclinical studies to evaluate the efficacy and safety of HDAC6 inhibitors in animal models.

Conclusion

CAS 1190305-31-7 is a valuable compound in the field of pharmaceutical research and development. Its selective inhibition of HDAC6 makes it a promising candidate for the treatment of various diseases. As research on HDAC6 inhibitors continues, it is likely that CAS 1190305-31-7 will play an important role in the discovery and development of new therapies.