CP-66,948, CAS 101189-47-3

CP-66,948, CAS 101189-47-3, Stock 285g, Assay 99.5%, White powder, Water 0.45%, Single Impurity 0.5%.

CP-66,948

CP-66,948 is a histamine H2-receptor antagonist with gastric antisecretory activity and mucosal protective properties. The affinity of CP-66,948 for the guinea pig atria histamine H2-receptor is 15 times greater than that of cimetidine and seven times greater than that of ranitidine. In vivo, the ED50 value for inhibition of gastric acid secretion in pylorus-ligated rats is 2 mg/kg intraduodenally.

Product Details:

Name: CP-66,948

CAS#: 101189-47-3

Chemical Formula: C13H20N6S

Exact Mass: 292.14702

Molecular Weight: 292.4

Elemental Analysis: C, 53.40; H, 6.89; N, 28.74; S, 10.97

Specification:

Synonym: CP66,948; CP 66,948; CP-66,948; CP 66948.

IUPAC/Chemical Name: 2-(N-Pentyl-N''-guanidino)-4-(2-methylimidazol-4-yl)thiazole

InChi Key: OZSXWXGDJLBJQO-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H20N6S/c1-3-4-5-6-15-12(14)19-13-18-11(8-20-13)10-7-16-9(2)17-10/h7-8H,3-6H2,1-2H3,(H,16,17)(H3,14,15,18,19)

SMILES Code: CCCCCNC(=N)Nc1scc(n1)c1cnc([nH]1)C

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: