Tegobuvir, CAS 1000787-75-6

Tegobuvir, CAS 1000787-75-6, Stock 486g, Assay 99.5%, White powder, Water 0.19%, Single Impurity 0.5%.

Tegobuvir

Tegobuvir, also known as GS-9190 and GS-333126, is a potent non-nucleoside polymerase inhibitor. Tegobuvir (GS-9190) had EC(50)s of <16 nM against genotype 1 and >100 nM for other genotypes tested. Tegobuvir is highly efficient in curing cells from HCV replicon and in delaying/preventing the development of drug resistance. GS-9190 represents a novel class of nonnucleoside polymerase inhibitors that interact with NS5B likely through involvement of the β-hairpin in the thumb subdomain.

Product Details:

Name: Tegobuvir

CAS#: 1000787-75-6

Chemical Formula: C25H14F7N5

Exact Mass: 517.1137

Molecular Weight: 517.4108

Elemental Analysis: C, 58.03; H, 2.73; F, 25.70; N, 13.54

Specification:

Synonym: GS-9190; GS 9190; GS9190; GS-333126; GS 333126; GS333126; Tegobuvir

IUPAC/Chemical Name: 5-((6-(2,4-bis(trifluoromethyl)phenyl)pyridazin-3-yl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine

InChi Key: XBEQSQDCBSKCHJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H14F7N5/c26-19-4-2-1-3-17(19)23-33-21-9-10-37(13-22(21)34-23)12-15-6-8-20(36-35-15)16-7-5-14(24(27,28)29)11-18(16)25(30,31)32/h1-11,13H,12H2

SMILES Code: FC1=CC=CC=C1C2=NC3=CN(CC4=NN=C(C5=CC=C(C(F)(F)F)C=C5C(F)(F)F)C=C4)C=CC3=N2

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: