主记录
Defactinib
- CAS
- 1073154-85-4
- PubChem CID
- 25117126
- SMILES
- CNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F
- 分子式
- C20H21F3N8O3S
- 分子量
- 510.502
- 精确分子量
- 510.1409
- InChI
- InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)
- InChIKey
- FWLMVFUGMHIOAA-UHFFFAOYSA-N
- LogP
- 2.3965
- TPSA
- 142.1
名称与别名
- Defactinib
- 1073154-85-4
- defactinibum
- Defacitinib
- VS-6063
- PF-04554878
- Defactinib [USAN]
- Defactinib [USAN:INN]
- Defactinib hydrochloride
- DEFACTINIB [INN]
- Defactinib (USAN/INN)
- RefChem:919757
- 53O87HA2QU
- UNII-53O87HA2QU
- C20H21F3N8O3S
- D0V6EV
- D0Y1UO
- DEFACTINIB [WHO-DD]
- MFCD25977806
- GTPL7910
- orb1183414
- orb1306800
- SCHEMBL1627234
- CHEMBL3137331
- FAK inhibitors (cancer), Pfizer
- Defactinib (PF-04554878)
- FWLMVFUGMHIOAA-UHFFFAOYSA-N
- 1345713-71-4
- BDBM418817
- DTXSID901025937