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CAS Number：1231732-20-9
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SMILES：CAS 1231732-20-9 is a chemical compound with the molecular formula C13H14ClN3O2S. It is also known by its trade name, Pazopanib hydrochloride. Pazopanib hydrochloride is a tyrosine kinase inhibitor used in the treatment of advanced renal cell carcinoma and soft tissue sarcoma.Chemical Properties:Pazopanib hydrochloride is a white or off-white crystalline powder with a molecular weight of 437.84 g/mol. It is soluble in water, ethanol, and methanol but insoluble in acetone and ethyl acetate. The melting point of Pazopanib hydrochloride is between 183??C to 187??C.Applications:Pazopanib hydrochloride is used in the treatment of advanced renal cell carcinoma and soft tissue sarcoma. Renal cell carcinoma is a type of kidney cancer that occurs in the lining of the small tubes in the kidney that filter blood and produce urine. Soft tissue sarcoma is a rare type of cancer that develops in the soft tissues of the body, including muscles, tendons, fat, and blood vessels.Pazopanib hydrochloride works by inhibiting the activity of tyrosine kinases, which are enzymes that play a role in the growth and spread of cancer cells. By blocking the activity of these enzymes, Pazopanib hydrochloride can slow down or stop the growth of cancer cells.In addition to its use in the treatment of cancer, Pazopanib hydrochloride has also been studied for its potential use in the treatment of other conditions, including ovarian cancer, breast cancer, and liver cancer.Conclusion:CAS 1231732-20-9, also known as Pazopanib hydrochloride, is a tyrosine kinase inhibitor used in the treatment of advanced renal cell carcinoma and soft tissue sarcoma. It works by inhibiting the activity of enzymes that play a role in the growth and spread of cancer cells. While studies are ongoing, Pazopanib hydrochloride may also have potential applications in the treatment of other types of cancer.