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CAS Number：918407-35-9
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SMILES：Avoralstat, CAS 918407-35-9Avoralstat, CAS?918407-35-9,?Stock?837g,?Assay?98.23%,?White powder,?Water?0.57%,?Single Impurity?0.82%.AvoralstatAvoralstat, also known as BCX-4161, is a potent and orally active Kallikrein inhibitor and Bradykinin inhibitor. Avoralstat may be potentially useful for treatment for Hereditary angioedema. Avoralstat inhibits plasma kallikrein and suppresses bradykinin production. Bradykinin is the mediator of acute swelling attacks in HAE patients.Product Details:Name: AvoralstatCAS#: 918407-35-9Chemical Formula: C28H27N5O5Exact Mass: 513.2012Molecular Weight: 513.554Elemental Analysis: C, 65.49; H, 5.30; N, 13.64; O, 15.58Specification:Synonym: BCX-4161; BCX 4161; BCX4161; AvoralstatIUPAC/Chemical Name: 3-{2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl}-6-[(cyclopropylmethyl)carbamoyl]pyridine-2-carboxylic acidInChi Key: TUWMKPVJGGWGNL-UHFFFAOYSA-NInChi Code: InChI=1S/C28H27N5O5/c1-3-16-12-21(26(34)32-18-8-6-17(7-9-18)25(29)30)20(13-23(16)38-2)19-10-11-22(33-24(19)28(36)37)27(35)31-14-15-4-5-15/h3,6-13,15H,1,4-5,14H2,2H3,(H3,29,30)(H,31,35)(H,32,34)(H,36,37)SMILES Code: O=C(C1=NC(C(NCC2CC2)=O)=CC=C1C3=CC(OC)=C(C=C)C=C3C(NC4=CC=C(C(N)=N)C=C4)=O)OAppearance: White powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certifications: