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CAS Number：1276105-89-5
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SMILES：CNX-1351, CAS 31276105-89-5CNX-1351, CAS?1276105-89-5,?Stock?653g,?Assay?99.52%,?White powder,?Water?0.29%,?Single Impurity?0.19%.CNX-1351CNX-1351 is a selective covalent Inhibitor of PI3K??. In an end point assay, CNX-1351 potently inhibited PI3K?? and was 20?400 times less potent against ??, ??, and ??. CNX-1351 inhibit PI3K?? signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX-1351 inhibits growth of cells dependent on PI3K??. CNX-1351 also inhibits PI3K?? signaling in vivo and bonds to p110??.Product Details:Name: CNX-1351CAS#: 1276105-89-5Chemical Formula: C30H35N7O3SExact Mass: 573.25221Molecular Weight: 573.71Elemental Analysis: C, 62.81; H, 6.15; N, 17.09; O, 8.37; S, 5.59Specification:Synonym:?CNX1351; CNX 1351; CNX-1351.IUPAC/Chemical Name:?1-(4-((2-(1H-indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-6-methylhept-5-ene-1,4-dioneInChi Key:?DLNUPKDFXMWRFP-UHFFFAOYSA-NInChi Code:?InChI=1S/C30H35N7O3S/c1-20(2)16-21(38)6-7-27(39)36-10-8-35(9-11-36)19-22-17-26-28(41-22)30(37-12-14-40-15-13-37)33-29(32-26)23-4-3-5-25-24(23)18-31-34-25/h3-5,16-18H,6-15,19H2,1-2H3,(H,31,34)SMILES Code:?C/C(C)=C/C(CCC(N1CCN(CC2=CC3=NC(C4=CC=CC5=C4C=NN5)=NC(N6CCOCC6)=C3S2)CC1)=O)=OAppearance:?solid powderPurity:?>99% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSO, not in waterShelf Life:?>2 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOStock Solution Storage:?0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code:?2934.99.9001Certifications: