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CAS Number：1285702-20-6
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SMILES：ML167, CAS?1285702-20-6ML167, CAS?1285702-20-6,?Stock?219g,?Assay?99.48%,?White powder,?Water?0.36%,?Single Impurity?0.16%.ML167ML167 is the first highly selective inhibitor of of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM for Clk4. The Cdc2-like kinases (Clk???s) and the dual-specificity tyrosine phosphorylation-regulated kinases (Dyrk???s) have specified roles in gene splicing. Specifically, the Clk class of enzymes has been shown to phosphorylate the serine- and arginine-rich (SR) proteins, which are a major component of the spliceosome.Product Details:Name: ML167CAS#: 1285702-20-6Chemical Formula: C19H17N3O3Exact Mass: 335.127Molecular Weight: 335.3566Elemental Analysis: C, 68.05; H, 5.11; N, 12.53; O, 14.31Specification:Synonym:?ML167; ML-167; ML 167; CID 44968231; CID44968231; CID-44968231; NCGC00188654; NCGC-00188654; NCGC 00188654IUPAC/Chemical Name:?(5-(4-(((5-methylfuran-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanolInChi Key:?ROCFOIBAEVAOLQ-UHFFFAOYSA-NInChi Code:?InChI=1S/C19H17N3O3/c1-12-2-4-14(24-12)9-20-19-16-8-13(3-6-17(16)21-11-22-19)18-7-5-15(10-23)25-18/h2-8,11,23H,9-10H2,1H3,(H,20,21,22)SMILES Code:?OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1Appearance:?Solid powderPurity:?>99% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOStock Solution Storage:?0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code:?2934.99.9001Certifications: