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CAS Number：1300031-49-5
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SMILES：GSK1210151A, CAS 1300031-49-5GSK1210151A, CAS?1300031-49-5,?Stock?663g,?Assay?99.38%,?White powder,?Water?0.31%,?Single Impurity?0.31%.GSK1210151AGSK1210151A, also known as I-BET151, is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. I-BET151 ( GSK1210151A ) shows good oral bioavailability in both the rat and minipig as well as demonstrating efficient suppression of bacterial induced inflammation and sepsis in a murine in vivo endotoxaemia model.Product Details:Name: GSK1210151ACAS#: 1300031-49-5Chemical Formula: C23H21N5O3Exact Mass: 415.16444Molecular Weight: 415.44Elemental Analysis: C, 66.49; H, 5.09; N, 16.86; O, 11.55Specification:Synonym:?IBET151; IBET-151; IBET 151; GSK1210151A; GSK-1210151A; GSK 1210151A.IUPAC/Chemical Name:?7-(3,5-dimethylisoxazol-4-yl)-8-methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-imidazo[4,5-c]quinolin-2(3H)-oneInChi Key:?VUVUVNZRUGEAHB-CYBMUJFWSA-NInChi Code:?InChI=1S/C23H21N5O3/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17/h5-11,13H,1-4H3,(H,26,29)/t13-/m1/s1SMILES Code:?O=C(N1[C@@H](C2=NC=CC=C2)C)NC3=C1C4=CC(OC)=C(C5=C(C)ON=C5C)C=C4N=C3Appearance:?Solid powderPurity:?>99% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSO, not in waterShelf Life:?>2 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOStock Solution Storage:?0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code:?2934.99.9001Certifications: