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CAS Number：1448169-71-8
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SMILES：CAS 1448169-71-8, Futibatinib (TAS-120)?CAS 1448169-71-8, Futibatinib (TAS-120)?,?Stock?817g,?Assay?99.2%,?White powder,?Water?0.4%,?Single Impurity?0.67%.Futibatinib (TAS-120)?Futibatinib, also known as TAS-120 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor TAS-120 selectively and irreversibly binds to and inhibits FGFR, which may result in the inhibition of both the FGFR-mediated signal transduction pathway and tumor cell proliferation, and increased cell death in FGFR-overexpressing tumor cells. FGFR is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival and its expression is upregulated in many tumor cell types.Product Details:Name: Futibatinib (TAS-120)CAS#: 1448169-71-8Chemical Formula: C22H22N6O3Exact Mass: 418.1753Molecular Weight: 418.46Elemental Analysis: C, 63.15; H, 5.30; N, 20.08; O, 11.47Specification:Synonym: TAS-120, TAS 120, TAS120; FutibatinibIUPAC/Chemical Name: 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-2-propen-1-oneInChi Key: KEIPNCCJPRMIAX-HNNXBMFYSA-NInChi Code: InChI=1S/C22H22N6O3/c1-4-19(29)27-8-7-15(12-27)28-22-20(21(23)24-13-25-22)18(26-28)6-5-14-9-16(30-2)11-17(10-14)31-3/h4,9-11,13,15H,1,7-8,12H2,2-3H3,(H2,23,24,25)/t15-/m0/s1SMILES Code: C=CC(N1C[C@@H](N2N=C(C#CC3=CC(OC)=CC(OC)=C3)C4=C(N)N=CN=C42)CC1)=OAppearance: Off-white to light beige solid powderPurity: >99% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certifications: