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CAS Number：1562338-42-4
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SMILES：Branaplam free base,?CAS 1562338-42-4:Branaplam free base,?CAS 1562338-42-4,?Stock?207g,?Assay?98.15%,?White powder,?Water?0.27%,?Single Impurity?0.21%.Branaplam free base,CAS 1562338-42-4Branaplam, also known as NVS-SM1 and LMI-070, is a highly potent, selective and orally active small molecule SMN2 splicing modulator as a potential treatment for SMA Type 1 (Spinal Muscular Atrophy) .NVS-SM1 works by increasing the amount of functional SMN protein produced by the ??back-up?? gene, SMN2, through modifying its splicing.Product Details:Name: Branaplam free baseCAS#: 1562338-42-4 (free base)Chemical Formula: C22H27N5O2Exact Mass: 393.2165Molecular Weight: 393.491Elemental Analysis: C, 67.15; H, 6.92; N, 17.80; O, 8.13Specification:Related CAS #: 1562338-42-4 (free base)? ?1562338-39-9 (HCl)? ?Branaplam mesylate? ??Synonym: NVS-SM1; NVS SM1; NVSSM1; LMI-070; LMI070; LMI 070; BranaplamIUPAC/Chemical Name: 5-(1H-pyrazol-4-yl)-2-[6-[(2,2,6,6-tetramethyl-4-piperidinyl)oxy]-3-pyridazinyl]-phenolInChi Key: STWTUEAWRAIWJG-UHFFFAOYSA-NInChi Code: InChI=1S/C22H27N5O2/c1-21(2)10-16(11-22(3,4)27-21)29-20-8-7-18(25-26-20)17-6-5-14(9-19(17)28)15-12-23-24-13-15/h5-9,12-13,16,27-28H,10-11H2,1-4H3,(H,23,24)SMILES Code: OC1=CC(C2=CNN=C2)=CC=C1C3=NN=C(OC4CC(C)(C)NC(C)(C)C4)C=C3Appearance: Solid powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSOShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: