Products

CAS Number：1631754-41-0
Catalog Number:
Chemcial Name:
MW(Molecular Weight)：
MF(Molecular Formula):
SMILES：CAS 1631754-41-0 (acetate): RezafunginCAS 1631754-41-0 (acetate): Rezafungin,?Stock?370g,?Assay?99.7%,?White powder, Water?0.27%,?Single Impurity?0.3%.RezafunginRezafungin (formerly CD101) is a new ??-glucan synthase inhibitor that is chemically related with anidulafungin. Rezafungin is a novel echinocandin (form of antifungal) with enhanced stability and pharmacokinetics that achieves high plasma drug exposure and allows for once weekly dose administration. Rezafungin has been shown comparable to other echinocandins, with activity against Candida spp. and Aspergillus spp. including subsets of echinocandin-resistant Candida auris and azole-resistant Aspergillus isolates.Product Details:Name: Rezafungin acetateCAS#: 1631754-41-0 (acetate)Chemical Formula: C65H88N8O19Exact Mass: 1,225.60Molecular Weight: 1,285.456Elemental Analysis: C, 60.73; H, 6.90; N, 8.72; O, 23.65Specification:Related CAS #: 1631754-41-0 (acetate)? ?1396640-59-7 (cation)? ?1396640-60-0 (TFA)? ?Rezafungin chloride? ??Synonym: Rezafungin; Biafungin; SP-3025; SP 3025; SP3025; CD101; CD-101; CD 101.IUPAC/Chemical Name: 2-(((2R,9S,11R,12R,14aS,15S,16S,20S,25aS)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6,20-bis((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxo-9-(4''-(pentyloxy)-[1,1':4',1''-terphenyl]-4-carboxamido)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-12-yl)oxy)-N,N,N-trimethylethan-1-aminium acetateInChi Key: MXMWJAPNUIKPGF-DPHATNFGSA-NInChi Code: InChI=1S/C63H84N8O17.C2H4O2/c1-8-9-10-28-87-45-25-21-40(22-26-45)38-13-11-37(12-14-38)39-15-17-42(18-16-39)56(80)64-46-31-48(76)61(88-29-27-71(5,6)7)68-60(84)52-53(77)34(2)32-70(52)63(86)50(36(4)73)66-59(83)51(55(79)54(78)41-19-23-43(74)24-20-41)67-58(82)47-30-44(75)33-69(47)62(85)49(35(3)72)65-57(46)81;1-2(3)4/h11-26,34-36,44,46-55,61,72-73,75-79H,8-10,27-33H2,1-7H3,(H5-,64,65,66,67,68,74,80,81,82,83,84);1H3,(H,3,4)/t34-,35+,36+,44+,46-,47-,48+,49?,50-,51?,52-,53-,54-,55-,61+;/m0./s1SMILES Code: CCCCCOC1=CC=C(C2=CC=C(C=C2)C3=CC=C(C=C3)C(N[C@H]4C[C@@H](O)[C@H](NC([C@@H]5[C@@H](O)[C@@H](C)CN5C([C@@H](NC(C(NC([C@@H]6C[C@@H](O)CN6C(C(NC4=O)[C@@H](C)O)=O)=O)[C@H](O)[C@@H](O)C7=CC=C(O)C=C7)=O)[C@@H](C)O)=O)=O)OCC[N+](C)(C)C)=O)C=C1.O=C(C)[O-]Appearance: Solid powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSOShelf Life: >3 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001