Products

CAS Number：2172875-40-8
Catalog Number:
Chemcial Name:
MW(Molecular Weight)：
MF(Molecular Formula):
SMILES：Paltusotine HCl, CAS: 2172875-40-8Paltusotine HCl, CAS: 2172875-40-8,?Stock?76g,?Assay?99.15%,?White powder,?EOS is one of TOP GMP manufacturerPaltusotinePaltusotine, also known as CRN00808, is a somatostatin receptor agonist. Paltusotine showed no direct inhibition of major cytochrome P450 enzymes or the hERG ion channel and had sufficient exposure in rats and excellent exposure in dogs upon oral dosing. In pharmacodynamic studies, Paltusotine dose-dependently suppressed growth hormone (GH) secretion induced by an exogenous growth-hormone-releasing hormone (GHRH) challenge in both male and female rats following a single oral dose and suppressed IGF-1 levels with repeated oral administration in both rats and dogs.Product Details:Name: Paltusotine HClCAS#: 2172875-40-8 (2HCl)Chemical Formula: C27H24Cl2F2N4OExact Mass:Molecular Weight: 529.41Elemental Analysis: C, 61.26; H, 4.57; Cl, 13.39; F, 7.18; N, 10.58; O, 3.02Specification:Related CAS #: 2361216-83-1 (HCl); 2172870-89-0 (free base)? ?2172875-40-8 (2HCl)? ??Synonym: Paltusotine hydrochloride; Paltusotine HCl; Paltusotine; CRN00808; CRN-00808; CRN 00808;IUPAC/Chemical Name: Benzonitrile, 3-(4-(4-amino-1-piperidinyl)-3-(3,5-difluorophenyl)-6-quinolinyl)-2-hydroxy-, hydrochloride (1:2)InChi Key: GVTGYFQUBMBIAE-UHFFFAOYSA-NInChi Code: InChI=1S/C27H22F2N4O.2ClH/c28-19-10-18(11-20(29)13-19)24-15-32-25-5-4-16(22-3-1-2-17(14-30)27(22)34)12-23(25)26(24)33-8-6-21(31)7-9-33;;/h1-5,10-13,15,21,34H,6-9,31H2;2*1HSMILES Code: N#CC1=CC=CC(C2=CC=C3N=CC(C4=CC(F)=CC(F)=C4)=C(N5CCC(N)CC5)C3=C2)=C1O.[H]Cl.[H]ClAppearance: Solid powderPurity:?>98% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSOShelf Life:?>3 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOStock Solution Storage:?0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Code:?2934.99.9001Certification: