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CAS Number：2407527-16-4
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SMILES：MK-0616, CAS 2407527-16-4MK-0616, CAS 2407527-16-4,??Stock?259g,?Assay?98.84%,?White powder, Water?0.24%, Single Impurity?0.15%.MK-0616Enlicitide chloride also known as MK0616, is an orally bioavailable PCSK9 Inhibitor. MK-0616 demonstrates significant LDL-C reduction. MK-0616 displayed high affinity (Ki = 5pM) for PCSK9 in vitro and sufficient safety and oral bioavailability preclinically to enable advancement into the clinic.Product Details:Name:?MK-0616CAS#: 2407527-16-4 (chloride)Chemical Formula: C82H110ClFN14O15Exact Mass: 0.00Molecular Weight: 1,586.313Elemental Analysis: C, 62.09; H, 6.99; Cl, 2.23; F, 1.20; N, 12.36; O, 15.13Specification:Synonym:?MK-0616; MK0616; MK 0616; Enlicitide chloride.IUPAC/Chemical Name:?L-Proline, L-alanyl-3-[[1-oxo-6-(trimethylammonio)hexyl]amino]-D-alanyl-3-[[(2-hydroxyacetyl)amino]methyl]-L-phenylalanyl-1-[6-[[[4-(2-aminoethyl)phenyl]methyl](3-carboxy-1-oxopropyl)amino]hexyl]-5-fluoro-L-tryptophyl-(3S)-3-hydroxy-L-prolyl-L-threonyl-O-methyl-L-tyrosyl-2-methyl-, (4??1),(8??4)-dilactam, cyclic (3??5)-ether, chloride (1:1)InChi Key:?KZFXQSLIAQMQRP-MQCRZNPVSA-OInChi Code:?InChI=1S/C81H104FN15O15S2/c1-50-73(101)87-63-40-54-15-10-14-52(35-54)13-8-9-31-112-68-22-27-94-72(68)77(105)90-71(51(2)98)76(104)89-64(39-53-16-19-61(109-7)20-17-53)79(107)95-26-11-24-81(95,3)80(108)83-25-34-114-49-56-36-55(48-113-33-23-69(99)86-66(75(103)85-50)43-84-70(100)47-111-30-12-29-110-32-28-97(4,5)6)37-60(38-56)96-46-59(91-92-96)45-93-44-57(41-65(78(94)106)88-74(63)102)62-42-58(82)18-21-67(62)93/h8-10,14-21,35-38,42,44,46,50-51,63-66,68,71-72,98H,11-13,22-34,39-41,43,45,47-49H2,1-7H3,(H7-,83,84,85,86,87,88,89,90,99,100,101,102,103,104,105,108)/p+1/b9-8+/t50-,51-,63+,64+,65+,66+,68+,71+,72+,81+/m1/s1SMILES Code:?FC=1C=C2C3=CN(C2=CC1)CCCCCCN4CC=5C=CC(=CC5)CCNC(=O)[C@@]6(C)N(C(=O)[C@H](CC7=CC=C(OC)C=C7)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@]8(N9C(=O)[C@](C3)(NC(=O)[C@](CC=%10C=C(C=CC%10)CNC(=O)CO[C@]8(CC9)[H])(NC(=O)[C@@H](CNC(CCCCC[N+](C)(C)C)=O)NC(=O)[C@H](C)NC(=O)CCC4=O)[H])[H])[H])[H])CCC6.[Cl-]Purity:?>98% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?To be determinedShelf Life:?>2 years if stored properlyDrug Formulation:?To be determinedStock Solution Storage:?0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code:?2934.99.9001