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  • CAS 53552-05-9: (?)-Bicuculline methochloride
    (World's Largest Pharmaceutical Supplier)

    CAS Number: 53552-05-9
    Stock: 268g
    Assay: 99.20%

Details

CAS Number:53552-05-9
Catalog Number:
Chemcial Name:
MW(Molecular Weight):
MF(Molecular Formula):
SMILES:(?)-Bicuculline methochloride, CAS 53552-05-9(?)-Bicuculline methochloride, CAS?53552-05-9,?Stock?268g,?Assay?99.20%,?Off-white or?White powder,?EOS Med Chem is big manufacturer of?(?)-Bicuculline methochloride.(?)-Bicuculline methochloride(?)-Bicuculline methochloride is an enantiomer of the GABA antagonist (+)-bicuculline methochloride. It increases the firing rate in rat cortical neurons similar to the (+) isomer but lacks GABA antagonist activity. (?C)-Bicuculline methochloride inhibits sodium-independent GABA receptor binding with an IC50 value of 500 ??M, which is approximately 100-fold less potent than (+)-bicuculline methochloride, but there is no stereoselectivity for sodium-dependent GABA receptor binding.Product Details:Name: (?)-Bicuculline methochlorideCAS#: 53552-05-9Chemical Formula: C21H20ClNO6Exact Mass: 417.0979Molecular Weight: 417.84Elemental Analysis: C, 60.37; H, 4.82; Cl, 8.48; N, 3.35; O, 22.97Specification:Synonym:?(?)-Bicuculline methochlorideIUPAC/Chemical Name:?(5R)-5-[(6S)-6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium, monochlorideInChi Key:?RLJKFAMYSYWMND-VOMIJIAVSA-MInChi Code:?InChI=1S/C21H20NO6.ClH/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m1./s1SMILES Code:?O=C(O1)C2=C(C=CC3=C2OCO3)[C@@]1([H])[C@@]4([H])C5=CC6=C(OCO6)C=C5CC[N+]4(C)C.[Cl-]Appearance:?Solid powderPurity:?>99% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSOShelf Life:?>3 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOStock Solution Storage:?0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code:?2934.99.9001Certifications:

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