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CAS Number：541550-19-0
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SMILES：Apilimod free base, CAS 541550-19-0Apilimod free base, CAS?541550-19-0,?Stock?268g,?Assay?99.20%,?Off-white or?White?powder,?EOS Med Chem is big manufacturer of Apilimod free base.Apilimod free baseApilimod, also known as STA-5326, is a IL-12/IL-23 inhibitor. Apilimod inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases - through the prevention of nuclear translocation of c-Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL-12 and IL-23 production by the drug.Product Details:Name: Apilimod free baseCAS#: 541550-19-0 (free base)Chemical Formula: C23H26N6O2Exact Mass: 418.2117Molecular Weight: 418.501Elemental Analysis: C, 66.01; H, 6.26; N, 20.08; O, 7.65Specification:Synonym: STA-5326; STA5326; STA 5326; LAM-002; LAM 002; LAM002; Apilimod free base.IUPAC/Chemical Name: (E)-4-(6-(2-(3-methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholinInChi Key: HSKAZIJJKRAJAV-KOEQRZSOSA-NInChi Code: InChI=1S/C23H26N6O2/c1-18-5-4-6-19(15-18)17-25-28-21-16-22(29-10-13-30-14-11-29)27-23(26-21)31-12-8-20-7-2-3-9-24-20/h2-7,9,15-17H,8,10-14H2,1H3,(H,26,27,28)/b25-17+SMILES Code: CC1=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=NC=CC=C4)=N2)=CC=C1Appearance: Solid powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certifications: