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CAS Number：887936-68-7
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SMILES：TemanogrelTemanogrel, CAS?887936-68-7,?Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of Temanogrel.TemanogrelTemanogrel, also known as APD791, is a highly selective 5-hydroxytryptamine2A receptor inverse agonist under development for the treatment of arterial thrombosis. APD791 displayed high-affinity binding to membranes (K(i) = 4.9 nM) and functional inverse agonism of inositol phosphate accumulation (IC(50) = 5.2 nM) in human embryonic kidney cells stably expressing the human 5-HT(2A) receptor. APD791 was greater than 2000-fold selective for the 5-HT(2A) receptor versus 5-HT(2C) and 5-HT(2B) receptors. APD791 inhibited 5-HT-mediated amplification of ADP-stimulated human and dog platelet aggregation (IC(50) = 8.7 and 23.1 nM, respectively).Product Details:Name: TemanogrelCAS#: 887936-68-7Chemical Formula: C24H28N4O4Exact Mass: 436.2111Molecular Weight: 436.512Elemental Analysis: C, 66.04; H, 6.47; N, 12.84; O, 14.66Specification:Synonym: APD791; APD-791; APD 791; TemanogrelIUPAC/Chemical Name: 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamideInChi Key: ZEOQUKRCASTCFR-UHFFFAOYSA-NInChi Code: InChI=1S/C24H28N4O4/c1-27-22(8-9-25-27)21-17-19(26-24(29)18-4-3-5-20(16-18)30-2)6-7-23(21)32-15-12-28-10-13-31-14-11-28/h3-9,16-17H,10-15H2,1-2H3,(H,26,29)SMILES Code: O=C(NC1=CC=C(OCCN2CCOCC2)C(C3=CC=NN3C)=C1)C4=CC=CC(OC)=C4Appearance: Solid powderPurity: >99% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certifications: