Introduction
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CAS 891859-12-4: Ceralifimod
(World's Largest Pharmaceutical Supplier)
CAS Number: 891859-12-4
Stock: 268g
Assay: 99.20%

Details
CAS Number:891859-12-4
Catalog Number:
Chemcial Name:
MW(Molecular Weight):
MF(Molecular Formula):
SMILES:CeralifimodCeralifimod, CAS?891859-12-4, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of Ceralifimod.CeralifimodCeralifimod, also known as ONO-4641, is a next-generation sphingosine 1-phosphate (S1P) receptor agonist selective for S1P receptors 1 and 5. In vitro, ONO-4641 showed highly potent agonistic activities versus S1P receptors 1 and 5 [half maximal effective concentration (EC(50) ) values of 0??0273 and 0??334?nM, respectively]. ONO-4641 decreased peripheral blood lymphocyte counts in rats by inhibiting lymphocyte egress from secondary lymphoid tissues. ONO-4641 prevented relapse of disease in a non-obese diabetic mouse model of relapsing-remitting EAE. ONO-4641 may provide therapeutic benefits in the treatment of multiple sclerosis.Product Details:Name: CeralifimodCAS#: 891859-12-4Chemical Formula: C27H33NO4Exact Mass: 435.24096Molecular Weight: 435.56Elemental Analysis: C, 74.45; H, 7.64; N, 3.22; O, 14.69Specification:Synonym: ONO-4641; ONO 4641; ONO4641; CeralifimodIUPAC/Chemical Name: 1-((6-((2-methoxy-4-propylbenzyl)oxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acidInChi Key: QDDQIPUKAXBMBX-UHFFFAOYSA-NInChi Code: InChI=1S/C27H33NO4/c1-4-5-19-6-7-22(26(12-19)31-3)17-32-24-10-11-25-18(2)21(9-8-20(25)13-24)14-28-15-23(16-28)27(29)30/h6-7,10-13,23H,4-5,8-9,14-17H2,1-3H3,(H,29,30)SMILES Code: CCCC1=CC=C(COC2=CC(CCC(CN3CC(C(O)=O)C3)=C4C)=C4C=C2)C(OC)=C1Appearance: Solid powderPurity: >99% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certifications:
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