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CAS Number：954126-98-8
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SMILES：Danirixin, CAS 954126-98-8Danirixin, CAS?954126-98-8,?Stock?205g,?Assay?99.2%,?Off-white powder,?EOS Med Chem is big manufacturer of?Danirixin.DanirixinDanirixin, also known as GSK1325756, is a potent, high-affinity, selective and reversible CXCR2 antagonist in development for treatment of chronic obstructive pulmonary disease. The dose-dependent inhibition of agonist-induced neutrophil activation following single and repeated once daily oral administration of danirixin suggests that this CXCR2 antagonist may have benefit in neutrophil-predominant inflammatory diseases.Product Details:Name: DanirixinCAS#: 954126-98-8Chemical Formula: C19H21ClFN3O4SExact Mass: 441.0925Molecular Weight: 441.9024Elemental Analysis: C, 51.64; H, 4.79; Cl, 8.02; F, 4.30; N, 9.51; O, 14.48; S, 7.25Specification:Synonym:?GSK1325756; GSK-1325756; GSK 1325756; Danirixin;IUPAC/Chemical Name:?(S)-1-(4-chloro-2-hydroxy-3-(piperidin-3-ylsulfonyl)phenyl)-3-(3-fluoro-2-methylphenyl)ureaInChi Key:?NGYNBSHYFOFVLS-LBPRGKRZSA-NInChi Code:?InChI=1S/C19H21ClFN3O4S/c1-11-14(21)5-2-6-15(11)23-19(26)24-16-8-7-13(20)18(17(16)25)29(27,28)12-4-3-9-22-10-12/h2,5-8,12,22,25H,3-4,9-10H2,1H3,(H2,23,24,26)/t12-/m0/s1SMILES Code:?ClC(C(S([C@H]1CCCNC1)(=O)=O)=C2O)=CC=C2NC(NC3=CC=CC(F)=C3C)=OAppearance:?Solid powderPurity:?>99% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?DMSO 5mg/mL with warm and sonicationShelf Life:?>2 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOStock Solution Storage:?0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code:?2934.99.9001Certifications: