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CAS Number：960203-27-4
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SMILES：Vortioxetine HBr, CAS 960203-27-4Vortioxetine HBr, CAS?960203-27-4,?Stock?455g,?Assay?99.34%,?White powder, EOS Med Chem is big manufacturer of?Vortioxetine HBr.Vortioxetine HBrVortioxetine, also known as Lu AA21004, is an atypical antidepressant, and was approved in 2013 by the U.S. FDA for the treatment of major depressive disorder (MDD) in adults. Vortioxetine is a so-called "serotonin modulator and stimulator." It has been shown to possess the following pharmacological actions: Serotonin transporter (SERT) blocker (i.e. serotonin reuptake inhibitor (SRI)) ?? Ki (binding affinity) = 1.6 nM, IC50 = 5.4 nM; Norepinephrine transporter (NET) blocker ?? Ki = 113 nM; 5-HT1A receptor high-efficacy partial agonist/near-full agonist ?? Ki = 15 nM, IA = 80%; 5-HT1B receptor partial agonist ?? Ki = 33 nM; 5-HT1D receptor antagonist ?? Ki = 54 nM; 5-HT3A receptor antagonist ?? Ki = 3.7 nM; 5-HT7 receptor antagonist ?? Ki = 19 nM.Product Details:Name: Vortioxetine HBrCAS#: 960203-27-4 (HBr)Chemical Formula: C18H23BrN2SExact Mass: 378.07653Molecular Weight: 379.36Elemental Analysis: C, 56.99; H, 6.11; Br, 21.06; N, 7.38; S, 8.45Specification:Related CAS #: 960203-27-4 (HBr)? ?508233-74-7 (free base)? ?1253056-29-9 (lactate)??Synonym: LuAA21004; LuAA 21004; LuAA-21004; Lu-AA21004; Lu AA21004; LuAA21004; AA21004; AA-21004; AA 21004; Vortioxetine, Vortioxetine Hydrobromide, BrintellixIUPAC/Chemical Name: 1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine hydrobromideInChi Key: InChI=1S/C18H22N2S.BrH/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20;/h3-8,13,19H,9-12H2,1-2H3;1HInChi Code: InChI=1S/C18H22N2S.BrH/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20;/h3-8,13,19H,9-12H2,1-2H3;1HSMILES Code: CC1=CC=C(SC2=CC=CC=C2N3CCNCC3)C(C)=C1.[H]BrAppearance: White to off-white solid powderPurity: >99% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO.Shelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certifications: