CAS 99533-80-9: K-252a

  • CAS 99533-80-9: K-252a

CAS 99533-80-9: K-252a
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  • CAS Number: 99533-80-9
  • Stock: 423g
  • Assay: 99.34%

K-252a, CAS 99533-80-9

K-252a, CAS 99533-80-9, Stock 423g, Assay 99.34%, White powder, EOS Med Chem is big manufacturer of K-252a.


K-252a, also known as SF 2370, is an alkaloid isolated from Nocardiopisis bacteria. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1.8 and 1.7 nmol/L, respectively). At higher concentrations it is also an efficient inhibitor of serine/threonine protein kinases (IC50 of 10 to 30 nmol/L).

Product Details:

Name: K-252a

CAS#: 99533-80-9

Chemical Formula: C27H21N3O5

Exact Mass: 467.1481

Molecular Weight: 467.481

Elemental Analysis: C, 69.37; H, 4.53; N, 8.99; O, 17.11


Related CAS #: 99533-80-9   97161-97-2    

Synonym: K-252a; K 252a; K252a; SF-2370; SF 2370; SF2370.

IUPAC/Chemical Name: methyl (5S,6R,8R)-6-hydroxy-5-methyl-13-oxo-5,6,7,8,14,15-hexahydro-13H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacene-6-carboxylate


InChi Code: InChI=1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18-,26+,27+/m1/s1

SMILES Code: [H][C@](C[C@]8(O)[C@@](OC)=O)(O[C@]78C)N5C3=C2N7C1=CC=CC=C1C2=C(CNC6=O)C6=C3C4=CC=CC=C45

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001