CAS 960527-22-4: Isothiafludine

  • CAS 960527-22-4: Isothiafludine

CAS 960527-22-4: Isothiafludine
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 960527-22-4
  • Stock: 423g
  • Assay: 99.34%

Isothiafludine, CAS 960527-22-4

Isothiafludine, CAS 960527-22-4, Stock 423g, Assay 99.34%, White powder, EOS Med Chem is big manufacturer of Isothiafludine.


Isothiafludine, also NZ-4 and W-28-F, is a HBV virus inhibitor that dramatically reduces the HBV DNA level in cells. During the hepatitis B virus (HBV) life cycle, nucleocapsid assembly is essential for HBV replication. Both RNA reverse transcription and DNA replication occur within the HBV nucleocapsid. HBV nucleocapsid is consisted of core protein (HBcAg), whose carboxy-terminal domain (CTD) contains an Arg-rich domain (ARD). The ARD of HBcAg does contribute to the encapsidation of pregenomic RNA (pgRNA).

Product Details:

Name: Isothiafludine

CAS#: 960527-22-4

Chemical Formula: C18H18FN3OS2

Exact Mass: 375.0875

Molecular Weight: 375.4804

Elemental Analysis: C, 57.58; H, 4.83; F, 5.06; N, 11.19; O, 4.26; S, 17.08


Synonym: Isothiafludine; NZ‐4; W-28-F; NZ 4; W 28 F; NZ4; W28F

IUPAC/Chemical Name: N-(4-fluorobenzyl)-5-isobutyl-[2,2'-bithiazole]-4-carboxamide


InChi Code: InChI=1S/C18H18FN3OS2/c1-11(2)9-14-15(22-18(25-14)17-20-7-8-24-17)16(23)21-10-12-3-5-13(19)6-4-12/h3-8,11H,9-10H2,1-2H3,(H,21,23)


Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001