CAS 957054-33-0 : Pictilisib mesylate

  • CAS 957054-33-0 : Pictilisib mesylate

CAS 957054-33-0 : Pictilisib mesylate
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  • CAS Number: 957054-33-0
  • Stock: 427g
  • Assay: 99.34%

Pictilisib mesylate, CAS 957054-33-0

Pictilisib mesylate, CAS 957054-33-0, Stock 427g, Assay 99.34%, White powderEOS Med Chem is big manufacturer of Pictilisib mesylate.


Pictilisib mesylate

Pictilisib, also known as Pictrelisib, GDC-0941, RG7321 and GNE0941 , is an orally bioavailable, and is a potent small-molecule thieno[3,2-d]pyrimidine inhibitor of the class I phosphatidylinositol 3 kinase (PI3K) isoforms p100alpha and p100delta with potential antineoplastic activity. GDC-0941 selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway; inhibition of tumor cell growth, motility and survival in susceptible tumor cell populations may result.


Product Details:

Name: Pictilisib mesylate

CAS#: 957054-33-0 (mesylate)

Chemical Formula: C25H35N7O9S4

Exact Mass:

Molecular Weight: 705.835

Elemental Analysis: C, 42.54; H, 5.00; N, 13.89; O, 20.40; S, 18.17


Specification:

Related CAS #: 957054-30-7 (free base)   957054-33-0 (mesylate)  

Synonym: Pictilisib mesylate; GDC-0941; GDC 0941; GDC0941; RG7321; RG-7321; RG 7321; GNE0941; GNE-0941; GNE 0941; Pictrelisib; Pictilisib

IUPAC/Chemical Name: 4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine dimesylate

InChi Key: RFRIKACSFOTIMU-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H27N7O3S2.2CH4O3S/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19;2*1-5(2,3)4/h2-4,13-14H,5-12,15H2,1H3,(H,24,27);2*1H3,(H,2,3,4)

SMILES Code: O=S(N1CCN(CC2=CC3=NC(C4=CC=CC5=C4C=NN5)=NC(N6CCOCC6)=C3S2)CC1)(C)=O.OS(=O)(C)=O.OS(=O)(C)=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: