CAS 956906-93-7: PF-04217903丨mesylate

  • CAS 956906-93-7: PF-04217903丨mesylate

CAS 956906-93-7: PF-04217903丨mesylate
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  • CAS Number: 956906-93-7
  • Stock: 427g
  • Assay: 99.34%

PF-04217903 mesylate, CAS 956906-93-7

PF-04217903 mesylate , CAS 956905-27-4, Stock 427g, Assay 99.34%, White powder, EOS Med Chem is big manufacturer of PF-04217903 mesylate .


PF-04217903 mesylate

PF-04217903 is a MET tyrosine kinase inhibitor, is also a n orally bioavailabe, small-molecule tyrosine kinase inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor PF-04217903 selectively binds to and inhibits c-Met, disrupting the c-Met signaling pathway, which may result in the inhibition of tumor cell growth, migration and invasion of tumor cells, and the induction of death in tumor cells expressing c-Met.


Product Details:

Name: PF-04217903 mesylate

CAS#: 956906-93-7 (mesylate)

Chemical Formula: C20H20N8O4S

Exact Mass:

Molecular Weight: 468.492

Elemental Analysis: C, 51.28; H, 4.30; N, 23.92; O, 13.66; S, 6.84


Specification:

Related CAS #: 956905-27-4 (free base)   956906-93-7 (mesylate)  

Synonym: PF-04217903 mesylate; PF04217903; PF 04217903; PF-04217903; PF4217903; PF-4217903; PF 4217903.

IUPAC/Chemical Name: 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol mesylate

InChi Key: HBEMHKVWZJTVOC-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H16N8O.CH4O3S/c28-7-6-26-12-15(9-22-26)17-10-21-18-19(23-17)27(25-24-18)11-13-3-4-16-14(8-13)2-1-5-20-16;1-5(2,3)4/h1-5,8-10,12,28H,6-7,11H2;1H3,(H,2,3,4)

SMILES Code: OCCN1N=CC(C2=CN=C3C(N(CC4=CC=C5N=CC=CC5=C4)N=N3)=N2)=C1.OS(=O)(C)=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: