CAS 955977-50-1: PI-3065

  • CAS 955977-50-1: PI-3065

CAS 955977-50-1: PI-3065
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 955977-50-1
  • Stock: 323g
  • Assay: 99.34%

PI-3065, CAS 955977-50-1

PI-3065, CAS 955977-50-1, Stock 323g, Assay 99.34%, White powder, EOS Med Chem is big manufacturer of PI-3065.


PI3065 is a p110δ isoform of phosphoinositide-3-OH kinase (PI(3)K) inhibitor. Inhibitors against the p110δ isoform of phosphoinositide-3-OH kinase (PI(3)K) have shown remarkable therapeutic efficacy in some human leukaemias. As p110δ is primarily expressed in leukocytes, drugs against p110δ have not been considered for the treatment of solid tumours. p110δ inactivation in regulatory T cells unleashes CD8(+) cytotoxic T cells and induces tumour regression. p110δ inhibitors can break tumour-induced immune tolerance and should be considered for wider use in oncology

Product Details:

Name: PI-3065

CAS#: 955977-50-1

Chemical Formula: C27H31FN6OS

Exact Mass: 506.22641

Molecular Weight: 506.64

Elemental Analysis: C, 64.01; H, 6.17; F, 3.75; N, 16.59; O, 3.16; S, 6.33


Synonym: PI-3065; PI3065; PI 3065.

IUPAC/Chemical Name: 6-[[4-(Cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-1H-indol-4-yl)-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine


InChi Code: InChI=1S/C27H31FN6OS/c28-21-3-4-22-20(5-6-29-22)24(21)26-30-23-15-19(17-33-9-7-32(8-10-33)16-18-1-2-18)36-25(23)27(31-26)34-11-13-35-14-12-34/h3-6,15,18,29H,1-2,7-14,16-17H2


Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001