CAS 954126-98-8: Danirixin

  • CAS 954126-98-8: Danirixin

CAS 954126-98-8: Danirixin
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 954126-98-8
  • Stock: 205g
  • Assay: 99.20%

Danirixin, CAS 954126-98-8

Danirixin, CAS 954126-98-8, Stock 205g, Assay 99.2%, Off-white powderEOS Med Chem is big manufacturer of Danirixin.


Danirixin, also known as GSK1325756, is a potent, high-affinity, selective and reversible CXCR2 antagonist in development for treatment of chronic obstructive pulmonary disease. The dose-dependent inhibition of agonist-induced neutrophil activation following single and repeated once daily oral administration of danirixin suggests that this CXCR2 antagonist may have benefit in neutrophil-predominant inflammatory diseases.

Product Details:

Name: Danirixin

CAS#: 954126-98-8

Chemical Formula: C19H21ClFN3O4S

Exact Mass: 441.0925

Molecular Weight: 441.9024

Elemental Analysis: C, 51.64; H, 4.79; Cl, 8.02; F, 4.30; N, 9.51; O, 14.48; S, 7.25


Synonym: GSK1325756; GSK-1325756; GSK 1325756; Danirixin;

IUPAC/Chemical Name: (S)-1-(4-chloro-2-hydroxy-3-(piperidin-3-ylsulfonyl)phenyl)-3-(3-fluoro-2-methylphenyl)urea


InChi Code: InChI=1S/C19H21ClFN3O4S/c1-11-14(21)5-2-6-15(11)23-19(26)24-16-8-7-13(20)18(17(16)25)29(27,28)12-4-3-9-22-10-12/h2,5-8,12,22,25H,3-4,9-10H2,1H3,(H2,23,24,26)/t12-/m0/s1

SMILES Code: ClC(C(S([C@H]1CCCNC1)(=O)=O)=C2O)=CC=C2NC(NC3=CC=CC(F)=C3C)=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: DMSO 5mg/mL with warm and sonication

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001