CAS 928134-65-0 : LCI-699

  • CAS 928134-65-0 : LCI-699

CAS 928134-65-0 : LCI-699
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 928134-65-0
  • Stock: 339g
  • Assay: 99.21%

LCI-699,CAS 928134-65-0

LCI-699  ,CAS 928134-65-0, Stock 339g, Assay 99.21%, White powder, Water 0.69%Single Impurity 0.10%。


Osilodrostat, also known as LCI699, is a potent inhibitor of 11β-hydroxylase, the enzyme which catalyzes the final step of cortisol synthesis. LCI699 may thus be a potential new treatment for all forms of Cushing's syndrome. Current evidence indicates that the novel aldosterone inhibitor LCI699 is an effective and well-tolerated antihypertensive agent that lowers plasma aldosterone concentration and produces a mild ACTH-stimulated cortisol response suppressive effect.

Product Details:

Name: Osilodrostat free base

CAS#: 928134-65-0 (free base)

Chemical Formula: C13H10FN3

Exact Mass: 227.08588

Molecular Weight: 227.237

Elemental Analysis: C, 68.71; H, 4.44; F, 8.36; N, 18.49


Synonym: LCI699; LCI 699; LCI-699; Osilodrostat; Osilodrostat free base

IUPAC/Chemical Name: (R)-4-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)-3-fluorobenzonitrile


InChi Code: InChI=1S/C13H10FN3/c14-12-5-9(6-15)1-3-11(12)13-4-2-10-7-16-8-17(10)13/h1,3,5,7-8,13H,2,4H2/t13-/m1/s1

SMILES Code: N#CC1=CC=C([C@H]2CCC3=CN=CN32)C(F)=C1

Appearance: Solid powder

Purity: >99%

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001