CAS 928134-65-0 : LCI-699
(World's Largest Pharmaceutical Supplier)
- CAS Number: 928134-65-0
- Stock: 339g
- Assay: 99.21%
LCI-699，CAS 928134-65-0
LCI-699 ，CAS 928134-65-0， Stock 339g， Assay 99.21%, White powder, Water 0.69%, Single Impurity 0.10%。
LCI-699
Osilodrostat, also known as LCI699, is a potent inhibitor of 11β-hydroxylase, the enzyme which catalyzes the final step of cortisol synthesis. LCI699 may thus be a potential new treatment for all forms of Cushing's syndrome. Current evidence indicates that the novel aldosterone inhibitor LCI699 is an effective and well-tolerated antihypertensive agent that lowers plasma aldosterone concentration and produces a mild ACTH-stimulated cortisol response suppressive effect.
Product Details:
Name: Osilodrostat free base
CAS#: 928134-65-0 (free base)
Chemical Formula: C13H10FN3
Exact Mass: 227.08588
Molecular Weight: 227.237
Elemental Analysis: C, 68.71; H, 4.44; F, 8.36; N, 18.49
Specification:
Synonym: LCI699; LCI 699; LCI-699; Osilodrostat; Osilodrostat free base
IUPAC/Chemical Name: (R)-4-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)-3-fluorobenzonitrile
InChi Key: USUZGMWDZDXMDG-CYBMUJFWSA-N
InChi Code: InChI=1S/C13H10FN3/c14-12-5-9(6-15)1-3-11(12)13-4-2-10-7-16-8-17(10)13/h1,3,5,7-8,13H,2,4H2/t13-/m1/s1
SMILES Code: N#CC1=CC=C([C@H]2CCC3=CN=CN32)C(F)=C1
Appearance: Solid powder
Purity: >99%
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
