CAS 892546-37-1: BIM-46187

CAS 892546-37-1: BIM-46187
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 892546-37-1
  • Stock: 268g
  • Assay: 99.20%

BIM-46187

BIM-46187，CAS  892546-37-1, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of BIM-46187.


BIM-46187

BIM-46187 is a pan G protein inhibitor. It specifically silences Gαq proteins by "freezing" Gαq in its empty pocket conformation, a conformational intermediate along the Gα activation pathway.


Product Details:

Name: BIM-46187

CAS#: 892546-37-1

Chemical Formula: C44H58N8O2S2

Exact Mass: 794.4124

Molecular Weight: 795.12

Elemental Analysis: C, 66.47; H, 7.35; N, 14.09; O, 4.02; S, 8.06


Specification:

Synonym: BIM-46187; BIM 46187; BIM46187; PH-064; PH 064; PH064;

IUPAC/Chemical Name: (2R,2'R)-3,3'-disulfanediylbis(2-amino-1-((S)-8-(cyclohexylmethyl)-2-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)propan-1-one)

InChi Key: GGDNOAWICIHSAW-KEAHXZLPSA-N

InChi Code: InChI=1S/C44H58N8O2S2/c45-35(43(53)51-23-21-49-27-37(33-17-9-3-10-18-33)47-41(49)39(51)25-31-13-5-1-6-14-31)29-55-56-30-36(46)44(54)52-24-22-50-28-38(34-19-11-4-12-20-34)48-42(50)40(52)26-32-15-7-2-8-16-32/h3-4,9-12,17-20,27-28,31-32,35-36,39-40H,1-2,5-8,13-16,21-26,29-30,45-46H2/t35-,36-,39-,40-/m0/s1

SMILES Code: O=C([C@@H](N)CSSC[C@H](N)C(N1[C@@H](CC2CCCCC2)C3=NC(C4=CC=CC=C4)=CN3CC1)=O)N5[C@@H](CC6CCCCC6)C7=NC(C8=CC=CC=C8)=CN7CC5

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: