Tradipitant, CAS 622370-35-8

Tradipitant, CAS 622370-35-8, Stock 891g, Assay 98.64%, White powder, Water 0.24%, Single Impurity 0.32%.

VLY-686 and LY686017

Tradipitant, also known as VLY-686 and LY686017, is the 2nd generation neurokinin-1 receptor antagonist, which showed activity in preclinical anxiety models. LY686017 may be a possible therapy for alcoholism. LY686017 can be also served as a suitable chemical platform for future imaging ligand development.

Product Details:

Name: Tradipitant

CAS#: 622370-35-8

Chemical Formula: C28H16ClF6N5O

Exact Mass: 587.09476

Molecular Weight: 587.9

Elemental Analysis: C, 57.20; H, 2.74; Cl, 6.03; F, 19.39; N, 11.91; O, 2.72

Specification:

Synonym: Tradipitant; LY686017; LY 686017; LY686017; VLY 686; VLY686; VLY686.

IUPAC/Chemical Name: (2-(1-(3,5-bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-chlorophenyl)methanone

InChi Key: CAVRKWRKTNINFF-UHFFFAOYSA-N

InChi Code: InChI=1S/C28H16ClF6N5O/c29-22-6-2-1-4-20(22)26(41)21-5-3-9-37-23(21)24-25(17-7-10-36-11-8-17)40(39-38-24)15-16-12-18(27(30,31)32)14-19(13-16)28(33,34)35/h1-14H,15H2

SMILES Code: O=C(C1=CC=CN=C1C2=C(C3=CC=NC=C3)N(CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)N=N2)C5=CC=CC=C5Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: