CAS 574013-66-4 : Fexaramine

CAS 574013-66-4 : Fexaramine
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  • CAS Number: 574013-66-4
  • Stock: 898g
  • Assay: 99.38%

Fexaramine, CAS 574013-66-4

Fexaramine, CAS 574013-66-4, Stock 898g, Assay 99.38%, White powderWater 0.21%, Single Impurity 0.41%.


Fexaramine is an agonist of the farnesoid X receptor (FXR), which is a bile acid-activated nuclear receptor that controls bile-acid synthesis, conjugation and transport, as well as lipid metabolism through actions in the liver and intestine. Fexaramine has 100-fold greater affinity for FXR than natural compounds and described the genomic targets and binding site on FXR. When administered orally to mice, fexaramine produced selective actions through FXR receptors in the intestines.

Product Details:

Name: Fexaramine

CAS#: 574013-66-4

Chemical Formula: C32H36N2O3

Exact Mass: 496.27259

Molecular Weight: 498.65

Elemental Analysis: C, 77.39; H, 7.31; N, 5.64; O, 9.66


Synonym: Fexaramine

IUPAC/Chemical Name: methyl (E)-3-(3-(N-((4'-(dimethylamino)-[1,1'-biphenyl]-4-yl)methyl)cyclohexanecarboxamido)phenyl)acrylate


InChi Code: InChI=1S/C32H36N2O3/c1-33(2)29-19-17-27(18-20-29)26-15-12-25(13-16-26)23-34(32(36)28-9-5-4-6-10-28)30-11-7-8-24(22-30)14-21-31(35)37-3/h7-8,11-22,28H,4-6,9-10,23H2,1-3H3/b21-14+


Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001