CAS 548486-59-5 : Ulodesine
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- CAS Number: 548486-59-5
- Stock: 268g
- Assay: 99.20%
Ulodesine
Ulodesine, CAS 548486-59-5, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of Ulodesine.
Ulodesine
Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout. Ulodesine is currently being developed by Biocryst. Ulodesine acts upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uric acid (sUA). Ulodesine has an IC(50) of 0.5 nM to PNP. BCX-4208 is currently undergoing early clinical investigation in psoriasis and gout.
Product Details:
Name: Ulodesine
CAS#: 548486-59-5
Chemical Formula: C12H16N4O3
Exact Mass: 264.12224
Molecular Weight: 264.28
Elemental Analysis: C, 54.54; H, 6.10; N, 21.20; O, 18.16
Specification:
Synonym: BCX4208, BCX 4208, BCX-4208, Ulodesine, DADMe-immucillin H
IUPAC/Chemical Name: 7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl)methyl)-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one
InChi Key: AFNHHLILYQEHKK-BDAKNGLRSA-N
InChi Code: InChI=1S/C12H16N4O3/c17-5-8-3-16(4-9(8)18)2-7-1-13-11-10(7)14-6-15-12(11)19/h1,6,8-9,13,17-18H,2-5H2,(H,14,15,19)/t8-,9+/m1/s1
SMILES Code: O=C1C(NC=C2CN3C[C@H](O)[C@@H](CO)C3)=C2N=CN1
Appearance: Solid powder
Purity: >99% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001