CAS 53910-25-1: Pentostatin
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Pentostatin, CAS 53910-25-1

Pentostatin, CAS 53910-25-1, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of Pentostatin.

Pentostatin

Pentostatin is classified as a purine analog, which is a type of antimetabolite. It mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, interfering with the cell's ability to process DNA. Cancer cells generally divide more often than healthy cells; DNA is highly involved in cell division (mitosis) and drugs which target DNA-related processes are therefore more toxic to cancer cells than healthy cells. Pentostatin is used to treat hairy cell leukemia. It is given by intravenous infusion once every two weeks for three to six months. Additionally, pentostatin has been used to treat steroid-refractory acute and chronic graft-versus-host disease. Pentostatin is also used in chronic lymphocytic leukemia (CLL) patients who have relapsed. (Source: http://en.wikipedia.org/wiki/Pentostatin)

Product Details:

Name: Pentostatin

CAS#: 53910-25-1

Chemical Formula: C11H16N4O4

Exact Mass: 268.11716

Molecular Weight: 268.27

Elemental Analysis: C, 49.25; H, 6.01; N, 20.88; O, 23.86

Specification:

Synonym: CI825; CI-825; CI 825; PD81565; PD-81565; PD 81565; covidarabine; deoxycoformycin; pentostatine. brand name: Nipent.

IUPAC/Chemical Name: (R)-3-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol

InChi Key: FPVKHBSQESCIEP-KDXUFGMBSA-N

InChi Code: InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9-/m0/s1

SMILES Code: O[C@H]1C2=C(N([C@H]3O[C@H](CO)[C@@H](O)C3)C=N2)N=CNC1

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: