CAS 2162120-87-6 : VH 032 amide-alkylC5-acid

  • CAS 2162120-87-6 : VH 032 amide-alkylC5-acid

CAS 2162120-87-6 : VH 032 amide-alkylC5-acid
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  • CAS Number: 2162120-87-6
  • Stock: 35g
  • Assay: 99.37%

VH 032 amide-alkylC5-acid, CAS 2162120-87-6

VH 032 amide-alkylC5-acid, CAS 2162120-87-6Stock 35g, Assay 99.37%, White powder.

VH 032 amide-alkylC5-acid

VH 032 amide-alkylC5-acid is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development. It incorporates an E3 ligase ligand plus alkylC5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. It is part of a range of functionalized tool molecules for PROTAC R&D.

Product Details:

Name: VH 032 amide-alkylC5-acid

CAS#: 2162120-87-6

Chemical Formula: C29H40N4O6S

Exact Mass: 572.2669

Molecular Weight: 572.721

Elemental Analysis: C, 60.82; H, 7.04; N, 9.78; O, 16.76; S, 5.60


Synonym: VH 032 amide-alkylC5-acid; VH 032 amide alkylC5-acid; VH 032 amide-alkylC5 acid; VH 032 amide alkylC5 acid;

IUPAC/Chemical Name: 7-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptanoic acid


InChi Code: InChI=1S/C29H40N4O6S/c1-18-25(40-17-31-18)20-12-10-19(11-13-20)15-30-27(38)22-14-21(34)16-33(22)28(39)26(29(2,3)4)32-23(35)8-6-5-7-9-24(36)37/h10-13,17,21-22,26,34H,5-9,14-16H2,1-4H3,(H,30,38)(H,32,35)(H,36,37)/t21-,22+,26-/m1/s1

SMILES Code: CC1=C(SC=N1)C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](NC(CCCCCC(O)=O)=O)C(C)(C)C)=O)=O)C=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001