CAS 152-58-9: Cortexolone

  •  CAS 152-58-9: Cortexolone

CAS 152-58-9: Cortexolone
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 152-58-9
  • Stock: 452g
  • Assay: 99.54%

Cortexolone, CAS 152-58-9

Cortexolone, CAS 152-58-9, Stock 452g, Assay 99.54%, Off-White powder, EOS Med Chem is big manufacturer of Cortexolone.


Cortexolone, also known as 11-deoxycortisol, is antiglucocorticoid agent. Cortexolone is also an active metabolite of Clascoterone (CB-03-01). In rat thymocytes, cortexolone competes for binding to glucocorticoid receptors, as identified on sucrose density gradients, and blocks the effect of triamcinolone acetonide (TA) on 2-deoxyglucose uptake.

Product Details:

Name: Cortexolone

CAS#: 152-58-9

Chemical Formula: C21H30O4

Exact Mass: 346.2144

Molecular Weight: 346.467

Elemental Analysis: C, 72.80; H, 8.73; O, 18.47


Synonym: Cortexolone; Reichstein's Substance S; SK&F 3050; SKF 3050; SKF3050; SKF-3050; Substance S; NSC-18317; Cortisol, 11-deoxy-; 11-deoxycortisol;

IUPAC/Chemical Name: (8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one


InChi Code: InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1

SMILES Code: O=C1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@](C(CO)=O)(O)CC[C@@]4([H])[C@]3([H])CCC2=C1

Appearance: Solid powder

Purity: >99.54% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001