CAS 1513857-77-6: Pemigatinib
(World's Largest Pharmaceutical Supplier)

Pemigatinib, CAS 1513857-77-6

Pemigatinib, CAS 1513857-77-6, Stock 239g, Assay 99.22%, Off-White powder, EOS Med Chem is big manufacturer of Pemigatinib.

Pemigatinib

Pemigatinib, also known as INCB054828, is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) types 1, 2, and 3 (FGFR1/2/3), with potential antineoplastic activity. FGFR inhibitor INCB054828 binds to and inhibits FGFR1/2/3, which may result in the inhibition of FGFR1/2/3-related signal transduction pathways. This inhibits proliferation in FGFR1/2/3-overexpressing tumor cells.

Product Details:

Name: Pemigatinib

CAS#: 1513857-77-6 (free base)

Chemical Formula: C24H27F2N5O4

Exact Mass: 487.2031

Molecular Weight: 487.5

Elemental Analysis: C, 59.13; H, 5.58; F, 7.79; N, 14.37; O, 13.13

Specification:

Synonym: Pemigatinib; INCB054828; INCB-054828; INCB 054828; INCB54828; INCB 54828; INCB-54828

IUPAC/Chemical Name: 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-[(morpholin-4-yl)methyl]-1,3,4,7-tetrahydro-2Hpyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one

InChi Key: HCDMJFOHIXMBOV-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H27F2N5O4/c1-4-30-21-14(11-27-23-16(21)9-15(28-23)13-29-5-7-35-8-6-29)12-31(24(30)32)22-19(25)17(33-2)10-18(34-3)20(22)26/h9-11H,4-8,12-13H2,1-3H3,(H,27,28)

SMILES Code: O=C1N(CC)C2=C3C(NC(CN4CCOCC4)=C3)=NC=C2CN1C5=C(F)C(OC)=CC(OC)=C5F

Appearance: Solid powder

Purity: >99.22% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: