CAS 1300031-49-5: GSK1210151A

  • CAS 1300031-49-5: GSK1210151A

CAS 1300031-49-5: GSK1210151A
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  • CAS Number: 1300031-49-5
  • Stock: 663g
  • Assay: 99.38%

GSK1210151A, CAS 1300031-49-5

GSK1210151A, CAS 1300031-49-5, Stock 663g, Assay 99.38%, White powderWater 0.31%, Single Impurity 0.31%.


GSK1210151A, also known as I-BET151, is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. I-BET151 ( GSK1210151A ) shows good oral bioavailability in both the rat and minipig as well as demonstrating efficient suppression of bacterial induced inflammation and sepsis in a murine in vivo endotoxaemia model.

Product Details:

Name: GSK1210151A

CAS#: 1300031-49-5

Chemical Formula: C23H21N5O3

Exact Mass: 415.16444

Molecular Weight: 415.44

Elemental Analysis: C, 66.49; H, 5.09; N, 16.86; O, 11.55


Synonym: IBET151; IBET-151; IBET 151; GSK1210151A; GSK-1210151A; GSK 1210151A.

IUPAC/Chemical Name: 7-(3,5-dimethylisoxazol-4-yl)-8-methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one


InChi Code: InChI=1S/C23H21N5O3/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17/h5-11,13H,1-4H3,(H,26,29)/t13-/m1/s1

SMILES Code: O=C(N1[C@@H](C2=NC=CC=C2)C)NC3=C1C4=CC(OC)=C(C5=C(C)ON=C5C)C=C4N=C3

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001