CAS 127408-31-5: Y-26763

CAS 127408-31-5: Y-26763
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  • CAS Number: 127408-31-5
  • Stock: 562g
  • Assay: 99.39%

Y-26763, CAS 127408-31-5

Y-26763, CAS 127408-31-5, Stock 562g, Assay 99.39%, White powderWater 0.35%, Single Impurity 0.26%.


Y-26763 is Kir6 (KATP) channel opener and active metabolite of Y-27152. Y-26763 protects the canine heart from a stunning injury through opening of the KATP channels. Y-26763 protects the working rat myocardium from ischemia/reperfusion injury through opening of KATP channels. Y-26763 activated K(ATP) channels in a reversible manner with a similar activity to diazoxide. Y-26763-induced inhibition of insulin release is dependent upon the activation of K(ATP) channels in human beta-cells.

Product Details:

Name: Y-26763

CAS#: 127408-31-5

Chemical Formula: C14H16N2O4

Exact Mass: 276.111

Molecular Weight: 276.292

Elemental Analysis: C, 60.86; H, 5.84; N, 10.14; O, 23.16


Synonym: Y-26763; Y 26763; Y26763.

IUPAC/Chemical Name: N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-hydroxyacetamide


InChi Code: InChI=1S/C14H16N2O4/c1-8(17)16(19)12-10-6-9(7-15)4-5-11(10)20-14(2,3)13(12)18/h4-6,12-13,18-19H,1-3H3/t12-,13+/m1/s1

SMILES Code: CC(N([C@H]1[C@H](O)C(C)(C)OC2=CC=C(C#N)C=C12)O)=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001