CAS 127373-66-4: Sivelestat free acid
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- CAS Number: 127373-66-4
- Stock: 266g
- Assay: 99.51%
Sivelestat free acid, CAS 127373-66-4
Sivelestat free acid, CAS 7127373-66-4, Stock 266g, Assay 99.51%, White powder, Water 0.26%, Single Impurity 0.23%.
Sivelestat free acid
Sivelestat, also known as ONO 5046, is an inhibitor of human neutrophil elastase. It is used in the treatment of acute respiratory failure. Preliminary studies show Sivelestat may also improve neuropathic pain.
Product Details:
Name: Sivelestat free acid
CAS#: 127373-66-4 (free acid)
Chemical Formula: C20H22N2O7S
Exact Mass: 434.1148
Molecular Weight: 434.463
Elemental Analysis: C, 55.29; H, 5.10; N, 6.45; O, 25.78; S, 7.38
Specification:
Synonym: ONO 5046; ONO5046; ONO-5046; LY544349; LY-544349; LY 544349; EI 546 sodium salt hydrate, Elaspol sodium salt hydrate, LY 544349 sodium salt hydrate, Sivelestat. Trade name: Elaspol.
IUPAC/Chemical Name: N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine
InChi Key: BTGNGJJLZOIYID-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24)
SMILES Code: O=C(O)CNC(C1=CC=CC=C1NS(=O)(C2=CC=C(OC(C(C)(C)C)=O)C=C2)=O)=O
Appearance: Solid powder
Purity: >99% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001