CAS 127373-66-4: Sivelestat free acid

CAS 127373-66-4: Sivelestat free acid
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 127373-66-4
  • Stock: 266g
  • Assay: 99.51%

Sivelestat free acid, CAS 127373-66-4

Sivelestat free acid, CAS 7127373-66-4, Stock 266g, Assay 99.51%, White powderWater 0.26%, Single Impurity 0.23%.

Sivelestat free acid

Sivelestat, also known as ONO 5046, is an inhibitor of human neutrophil elastase. It is used in the treatment of acute respiratory failure. Preliminary studies show Sivelestat may also improve neuropathic pain.

Product Details:

Name: Sivelestat free acid

CAS#: 127373-66-4 (free acid)

Chemical Formula: C20H22N2O7S

Exact Mass: 434.1148

Molecular Weight: 434.463

Elemental Analysis: C, 55.29; H, 5.10; N, 6.45; O, 25.78; S, 7.38


Synonym: ONO 5046; ONO5046; ONO-5046; LY544349; LY-544349; LY 544349; EI 546 sodium salt hydrate, Elaspol sodium salt hydrate, LY 544349 sodium salt hydrate, Sivelestat. Trade name: Elaspol.

IUPAC/Chemical Name: N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine


InChi Code: InChI=1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24)

SMILES Code: O=C(O)CNC(C1=CC=CC=C1NS(=O)(C2=CC=C(OC(C(C)(C)C)=O)C=C2)=O)=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001