CAS 1271726-51-2 : Glutathione arsenoxide
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Glutathione arsenoxide, CAS 1271726-51-2

Glutathione arsenoxide, CAS 1271726-51-2, Stock 590g, Assay 99.25%, White powder, Water 0.39%, Single Impurity 0.36%.

Glutathione arsenoxide

Glutathione arsenoxide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. Glutathione arsenoxide has potential anti-angiogenic capability with application in cancer where tumour metastasis relies on neo-vascularisation. As GSAO arsenic is trivalent, the arsenoxide moiety reacts with appropriately spaced cysteine residues on adenine nucleotide translocase mitochondrial membrane protein.

Product Details:

Name: Glutathione arsenoxide

CAS#: 1271726-51-2

Chemical Formula: C18H25AsN4O9S

Exact Mass: 548.0558

Molecular Weight: 548.3986

Elemental Analysis: C, 39.42; H, 4.60; As, 13.66; N, 10.22; O, 26.26; S, 5.85

Specification:

Synonym: Glutathione arsenoxide; GSAO;

IUPAC/Chemical Name: N5-((R)-1-((carboxymethyl)amino)-3-((2-((4-(dihydroxyarsanyl)phenyl)amino)-2-oxoethyl)thio)-1-oxopropan-2-yl)-L-glutamine

InChi Key: ADJQAKCDADMLPP-STQMWFEESA-N

InChi Code: InChI=1S/C18H25AsN4O9S/c20-12(18(29)30)5-6-14(24)23-13(17(28)21-7-16(26)27)8-33-9-15(25)22-11-3-1-10(2-4-11)19(31)32/h1-4,12-13,31-32H,5-9,20H2,(H,21,28)(H,22,25)(H,23,24)(H,26,27)(H,29,30)/t12-,13-/m0/s1

SMILES Code: O=C(O)CNC([C@H](CSCC(NC1=CC=C([As](O)O)C=C1)=O)NC(CC[C@@H](C(O)=O)N)=O)=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: