T011, CAS 1001288-58-9

T011, CAS 1001288-58-9, Stock 134g, Assay 99.7%, White powder, Water 0.34%, Single Impurity 0.3%.

T011

T011 is an anti-inflammatory and anti-fibrotic agent that has been reported to attenuate organ damage in diabetic rats with cardiomyopathy and nephropathy. In diabetic rats, FT011 reduced retinal leukostasis, microglial density and mRNA levels of intercellular adhesion molecule-1 (ICAM-1). In Müller cells, FT011 reduced diabetes-induced gliosis and vascular endothelial growth factor (VEGF) immunolabeling and the hyperglycaemic-induced increase in ICAM-1, monocyte chemoattractant protein-1, CCL20, cytokine-induced neutrophil chemoattractant-1, VEGF and IL-6.

Product Details:

Name: FT011

CAS#: 1001288-58-9

Chemical Formula: C20H17NO5

Exact Mass: 351.1107

Molecular Weight: 351.358

Elemental Analysis: C, 68.37; H, 4.88; N, 3.99; O, 22.77

Specification:

Synonym: FT011; FT0 11; FT0-11

IUPAC/Chemical Name: 2-(3-Methoxy-4-propargyloxycinnamoyl)aminobenzoic acid

InChi Key: UIWZIDIJCUEOMT-PKNBQFBNSA-N

InChi Code: InChI=1S/C20H17NO5/c1-3-12-26-17-10-8-14(13-18(17)25-2)9-11-19(22)21-16-7-5-4-6-15(16)20(23)24/h1,4-11,13H,12H2,2H3,(H,21,22)(H,23,24)/b11-9+

SMILES Code: O=C(O)C1=CC=CC=C1NC(/C=C/C2=CC=C(OCC#C)C(OC)=C2)=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: