CAS 1001288-58-9 : T011
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- CAS Number: 1001288-58-9
- Stock: 134g
- Assay: 99.70%
T011, CAS 1001288-58-9
T011, CAS 1001288-58-9, Stock 134g, Assay 99.7%, White powder, Water 0.34%, Single Impurity 0.3%.
T011 is an anti-inflammatory and anti-fibrotic agent that has been reported to attenuate organ damage in diabetic rats with cardiomyopathy and nephropathy. In diabetic rats, FT011 reduced retinal leukostasis, microglial density and mRNA levels of intercellular adhesion molecule-1 (ICAM-1). In Müller cells, FT011 reduced diabetes-induced gliosis and vascular endothelial growth factor (VEGF) immunolabeling and the hyperglycaemic-induced increase in ICAM-1, monocyte chemoattractant protein-1, CCL20, cytokine-induced neutrophil chemoattractant-1, VEGF and IL-6.
Chemical Formula: C20H17NO5
Exact Mass: 351.1107
Molecular Weight: 351.358
Elemental Analysis: C, 68.37; H, 4.88; N, 3.99; O, 22.77
Synonym: FT011; FT0 11; FT0-11
IUPAC/Chemical Name: 2-(3-Methoxy-4-propargyloxycinnamoyl)aminobenzoic acid
InChi Key: UIWZIDIJCUEOMT-PKNBQFBNSA-N
InChi Code: InChI=1S/C20H17NO5/c1-3-12-26-17-10-8-14(13-18(17)25-2)9-11-19(22)21-16-7-5-4-6-15(16)20(23)24/h1,4-11,13H,12H2,2H3,(H,21,22)(H,23,24)/b11-9+
SMILES Code: O=C(O)C1=CC=CC=C1NC(/C=C/C2=CC=C(OCC#C)C(OC)=C2)=O
Appearance: Solid powder
Purity: >99% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001