Quizartinib, CAS 950769-58-1

  • Quizartinib, CAS 950769-58-1

Quizartinib, CAS 950769-58-1
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 950769-58-1
  • Stock: 1.64kg
  • Assay: 98.63%

Quizartinib, CAS 950769-58-1

Quizartinib, CAS 950769-58-1Stock 1642g, Assay 98.63%, White powderWater 0.34%, Single Impurity 0.8%.


Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell proliferation and apoptosis. Mutations in FLT3, resulting in constitutive activation, are the most frequent genetic alterations in acute myeloid leukemia (AML) and occur in approximately one-third of AML cases.

Product Details:

Name: Quizartinib freebase

CAS#: 950769-58-1 (free base)

Chemical Formula: C29H32N6O4S

Exact Mass: 560.2206

Molecular Weight: 560.673

Elemental Analysis: C, 62.13; H, 5.75; N, 14.99; O, 11.41; S, 5.72


Synonym: AC220; AC 220; AC-220; AC010220; AC-010220; AC 010220; AC010220; Quizartinib.

IUPAC/Chemical Name: 1-(5-(tert-butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea


InChi Code: InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)


Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001