PF-562271 HCl, CAS 939791-41-0

  • PF-562271 HCl, CAS 939791-41-0

PF-562271 HCl, CAS 939791-41-0
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  • CAS Number: 939791-41-0
  • Stock: 1.49kg
  • Assay: 98.46%

PF-562271 HCl, CAS 939791-41-0

PF-562271 HCl, CAS 939791-41-0Stock 1485g, Assay 98.46%, White powderWater 0.29%, Single Impurity 0.17%.

PF-562271 HCl

PF-562271, also known as PF-562,271 and PF-271, is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF-562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline-rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival.

Product Details:

Name: PF-562271 HCl

CAS#: 939791-41-0 (HCl)

Chemical Formula: C21H21ClF3N7O3S

Exact Mass:

Molecular Weight: 543.95

Elemental Analysis: C, 46.37; H, 3.89; Cl, 6.52; F, 10.48; N, 18.03; O, 8.82; S, 5.89


Synonym: PF562271; PF562271; PF-562271; PF562,271; PF562,271; PF-562,271; PF-00562271; PF00562271; PF 00562271; PF562271 hydrochloride. PF271, PF-271, PF 271

IUPAC/Chemical Name: N-methyl-N-(3-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamide hydrochloride


InChi Code: InChI=1S/C21H20F3N7O3S.ClH/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16;/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30);1H

SMILES Code: CS(=O)(N(C)C1=NC=CC=C1CNC2=NC(NC3=CC4=C(NC(C4)=O)C=C3)=NC=C2C(F)(F)F)=O.[H]Cl

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001